99. Terrorism.

98. Gingivitis.

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97. Peeling paint.

96. Potential asteroid strikes.

95. Deaths caused by "extreme" sports.

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94. Inability to get into desirable nightclubs.

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93. Snakebites.

92. Missed child support payments.

91. Defamatory online smears.

90. Attacks by charismatic megafauna.

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89. Unintentional ingestion of poison.

88. Tardiness.

87. Botched plastic surgery.

86. Ugly clothes.

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85. Structure fires.

84. Wildfires.

83. Built-in obsolescence of electronic devices.

82. Dog or cat bites.

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81. Nothing good to watch on TV.

80. Rats.

79. Light pollution.

78. Muggings.

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77. Drowning.

76. Airline delays.

75. Simple trips and falls.

74. Sexism in media and entertainment.

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73. Racism in media and entertainment.

72. Traumatic brain injury associated with sports.

71. Prison gangs.

70. Surly or rambunctious teenagers.

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69. Street gangs.

68. Sophisticated international organized criminal enterprises.

67. Food-borne illness.

66. Joint disease.

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65. Orbiting space pollution.

64. Loss of wetlands.

63. Credit card fraud.

62. Cultural snobbery.

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61. Non-fatal STDs.

60. Insider trading.

59. Police brutality.

58. Factory farms.

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57. Hurricanes.

56. Erectile dysfunction.

55. Gentrification.

54. This weather we're having.

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53. Bullies.

52. Crying babies.

51. Too many hours spent sitting.

50. Cockblocking.

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49. Narcissism.

48. Bureaucracy.

47. Alzheimer's.

46. The general sense of ennui that accompanies modernity.

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45. Lack of knowledge about the long-term effects of industrial chemicals.

44. The degradation of our nation's bridges, highways, and other infrastructure.

43. Drought.

42. Drug addiction.

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41. Alcoholism.

40. Low wage dead end jobs.

39. Everything too expensive.

38. AIDS

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37. Gerrymandering.

36. Inability to enact meaningful campaign finance reform.

35. A criminal justice system that favors the rich.

34. Air pollution.

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33. Water pollution

32. Student debt.

31. The mathematical impossibility of an adequately funded retirement.

30. Lack of socioeconomic mobility.

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29. New and dangerous varieties of infectious disease.

28. Rape.

27. Unemployment.

26. Diabetes.

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25. Unwise deregulation of financial markets.

24. Military non-fatal casualties in foreign wars.

23. Military fatalities in foreign wars.

22. Civilian non-fatal casualties in foreign wars.

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21. Civilian fatalities in foreign wars.

20. Homelessness.

19. Rampant obesity.

18. Auto accidents.

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17. Government eavesdropping.

16. Mental illness.

15. Lack of health insurance.

14. Suicide.

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13. A low quality and unequal public educational system.

12. Sexism in society at large.

11. Racism in society at large.

10. Too many guns.

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9. The misguided war on drugs.

8. Mass extinction of nonhuman species.

7. Loneliness.

6. Cancer.

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5. A loss of perspective on what is and is not important.

4. Heart disease.

3. Global warming.

2. Poverty.

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1. Sellouts.

[Image by Jim Cooke. Thanks, JRL.]